Alpha-2-macroglobulin, a Native and Powerful Proteinase Inhibitor, Prevents Cartilage Degeneration Disease by Inhibiting Majority of Catabolic Enzymes and Cytokines
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Alpha-2-macroglobulin:
A Physiological Guardian
Alpha-2-macroglobulin (a2M), a key member of alpha macroglobulin superfamily
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Identification of
Alpha-2-macroglobulin as a Master Inhibitor of Cartilage-Degrading Factors That Attenuates the Progression of Post traumatic Osteoarthritis (continue)
Alpha-2-macroglobulin is unique in possessing a multi-modal mechanism of action — non-specific protease inhibition, cytokine and growth factor modulation, and gene regulation. (continue)